Abstract
Summary
Changes in canine renal blood flow in response to intra-arterial injections of angiotensin were studied in innervated and chronically denervated kidneys under a variety of conditions. In all cases, angiotensin decreased renal blood flow. Angiotensin was equally effective in reducing renal blood flow in innervated kidneys, reserpinized kidneys, kidneys treated with lidocaine, and in chronically denervated kidneys. These results suggest that the renal vasoconstrictor action of angiotensin is largely independent of an intact renal vasomotor innervation.
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