Abstract
Summary
Epinephrine (E), norepinephrine (NE), and isoproterenol (ISO), contract isolated strips of rabbit aorta and vena cava. ISO is less potent than either E or NE. In all cases, the contractions are considerably reduced by phenoxybenzamine and not significantly altered by pronethalol. It is concluded that the contractile response to the three catecholamines is initiated by alpha-adrenergic receptors in venous as well as arterial strips.
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