Abstract
Summary
Dose-response data are reported for three serum antigens evaluated in a rapid screening test suitable for evaluation of anti-inflammatory compounds. Canine serum, when administered subcutaneously, was found to be a more useful antigen than bovine or equine sera for producing an immune response with rapid onset and relatively short duration. The test model described may be completed in 12 days. Dexamethasone, dexamethasone 21-phosphate, prednisolone, and indomethacin were successful in reducing the canine serum uveitis.
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