Abstract
Summary
Rat liver slices from fed or fasted animals do not have the ability to conduct cation transport when subjected to anoxia. However, anoxic cation transport can be stimulated in liver slices of fed animals when slices are preincubated under O2. In addition, anoxic cation transport can be stimulated by incubation of slices in pyruvate, oxalacetate, or phosphoenolpyruvate. These conditions did not stimulate anoxic cation transport in liver of fasted animals. All attempts at metabolite reconstitution also failed to elicit anoxic cation transport in liver of fasted animals.
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