Abstract
Summary
Plasma HGH, FFA, glucose, and a-amino nitrogen levels were determined in seven young men after heparin administration. Plasma FFA increased rapidly, followed by a gradual fall. Corresponding to the fall of plasma FFA, a marked rise of plasma HGH was demonstrated. This HGH rise was diminished when plasma FFA was kept elevated, or when glucose was given. From these results it was concluded that the fall of plasma FFA could stimulate HGH secretion as in the case of falling blood glucose values and that the fluctuation of plasma FFA could be one of the factors regulating the secretion of HGH.
The authors express their thanks to Prof. Kiku Nakao and Dr. Kazuo Shizume (Chief, Dept. of Endocrinology, Toranomon Hospital, Akasaka, Tokyo) for their advice and encouragement. Technical assistance of Miss Junko Shibazaki and Miss Miki Komiyama is greatly appreciated.
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