Abstract
Summary
Seven Swedish families, altogether 28 persons, were kept under observation for 2–7 months for the spread of EBV infections. The seven index cases, aged 4–20 years, all presented a typical clinical picture of IM with atypical cells and heterophile antibodies. They all displayed increases in EBV antibody titers. Seven of the 21 contacts had significant EBV antibody titer rises, indicating an EBV infection. Five of these seven individuals also had atypical cells or heterophile antibodies. One case was found of a concomitant titer rise to EBV and CMV. Sera from all but 3 of the 28 persons stimulated the growth of bone marrow colonies in vitro.
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