Abstract
Summary
The thymocyte-agglutination titer of ALS raised in rabbits against mouse lymphoid cells correlated with immunosuppressive potency of antisera harvested after one or two immunizing injections. However, when ALS preparations were harvested from rabbits given multiple booster injections of lymphocytes the thymocyte-agglutination titer remained elevated whereas immunosuppressive potency progressively declined. The capacity of ALS preparations to stimulate mouse lymphocytes in vitro did not correlate with the immunosuppressive potency of these antisera.
The technical assistance of J. Parker and M. Langley is gratefully acknowledged.
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