Abstract
Summary
Malaria was induced in rhesus monkeys with Plasmodium knowlesi. Intracellular concentrations of sodium and potassium were studied in erythrocytes, muscle, and liver. The calculated content of sodium increased significantly in these cells, the magnitude of change being greater in erythrocytes than in liver and muscle. The intracellular potassium content decreased in erythrocytes, did not change in muscle, and increased in liver. These data provide additional evidence of a circulating toxic substance in malaria.
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