Abstract
Summary
Determination of the electrophoretic mobility of PSL particles in increasing concentration of PLG showed an unexpectedly high positive mobility at a coverage corresponding to one monolayer. This elevated mobility was tentatively ascribed to a particular orientation of the adsorbing PLG molecules due to interaction with the PSL surface. Other surfaces examined suggest that the effect is produced by hydrophobic surfaces. The mobility changes were shown to be correlated with changes in the organ distribution of PSL particles injected into rats.
It is a pleasure to acknowledge the enthusiastic technical help of Mr. Craig A. Warren. The work was supported in part by grants from The John A. Hartford Foundation, Inc., the National Institutes of Health (Grant No. AL 07161-02), and the Office of Naval Research. [Grant No. Nonr-4170 (00, NR 301-740)].
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