Abstract
Summary
Rat thymus cells were used as target cells in Jerne agar plaque technique to detect and enumerate antibody-forming cells of mouse stimulated with this antigen. 51Cr-labeled rat thymus cells were also used in these experiments to carry out plaque assay autoradiographically. The techniques demonstrated complement-dependent cytolytic plaques caused by antibodies released from immune mouse spleen cells and could be used to investigate kinetics of antibody-forming cells.
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