Abstract
Summary
Gonadotropin was isolated from human term placenta by precipitation with acetone and ammonium sulfate and by gel filtration on Sephadex column. The product was designated as human placental gonadotropin (HPG). The HPG induced an increase in uterine weight without producing ovarian hemorrhages. The result suggests that HPG and human chorionic gonadotropin may be different forms of chorionic gonadotropin.
The author wishes to express his gratitude to Mr. Gilbert Martinez and Mrs. Maria T. Elvira for their technical assistance and to Dr. F. Fuchs for making available the placenta used in this study.
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