Abstract
Summary
Increased hypophyseal mass which follows castration in immature male rats, was due to cellular hypertrophy at 50 days of age and hyperplasia at 65 days of age. Thiouracil (0.1%) had no significant effect on hypophyseal protein, RNA, or DNA in the immature rat fed the drug for 40 days. However thiouracil enhanced some of the effects of castration on the pituitary.
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