Abstract
Summary
The mouse-adapted measles virus induced plaques of different morphology from the parental Edmonston measles virus in primary green monkey kidney cells and in stable cell lines (BSC-1 and Vero) derived from this tissue. The CPE produced by the mouse-adapted measles appeared earlier in the Vero and primary green monkey kidney cells than in the BSC-1 cells. Actinomycin D increased the yield of the mouse-adapted measles in BSC-1 cells but not in Vero cells. This correlates well with the production of interferon in BSC-1 cells and lack of production of interferon in Vero cells following inoculation of the cultures with the mouse-adapted measles virus.
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