Abstract
Summary
Anterior pituitary glands from rats sacrificed during estrus were significantly heavier than those from rats killed during either proestrus or diestrus but not metestrus. Failure to detect concurrent alterations in anterior pituitary DNA content indicated cellular hypertrophy as the means by which these weight changes occurred. Total anterior pituitary RNA and RNA/DNA ratio were significantly increased at estrus suggesting increased protein synthetic activity at this time.
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