Abstract
Summary
Mice treated with endotoxin 18 hr earlier had markedly reduced liver carbohydrate, but with cortisone under the same conditions the level was more than doubled. Elipten exerted no apparent effect on the carbohydrate levels in normal mice, but very nearly eliminated the deposition of glycogen after the mice were treated with cortisone. The effect of endotoxemia on the liver carbohydrate was enhanced by Elipten, and ameliorated slightly by cortisone alone or in combination with Elipten.
The author thanks Dr. J. J. Chart of CIBA for the supply of Elipten. This investigation was supported by USPHS research grant AI-06767 from the National Institute of Allergy and Infectious Diseases.
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