Abstract
Summary
The sulfoxides and sulfone of biocytin have been synthesized by treatment of biocytin in acetic acid with hydrogen peroxide at equimolar or tenfold higher concentrations, respectively. The derivatives were characterized by microanalyses, melting points, infrared spectra, and chromatographic mobilities. The d-sulfoxide predominates from chemical synthesis and is probably the compound which was found earlier in human urine. Biocytinase in rat blood can catalyze cleavage of both sulfoxide and sulfone forms
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