Abstract
Summary
Direct agglutination of erythrocytes, mixed hemagglutination, and FA techniques were used to study antigens in four cultures of canine and two of human origin. All cultures maintained species-specific antigens. Dog kidney cell cultures apparently acquired heterologous-species antigens during primary growth. These were antigens shared with human and sheep erythrocytes. Nonspe-cies-specific common antigens were found in the primary and tertiary dog kidney cells and the three continuous lines. The indirect FA test, using uncultured dog kidney tissue antiserum, correlated well with the indirect hemagglutination method.
We thank the Veterinary Department of the Fission Products Inhalation Program for obtaining canine tissues for us and Dr. Antone Brooks for the chromosome study of the two canine continuous lines.
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