Glucosamine Acetoacetate Condensate II. Isolation and Identification from Human Diabetic Urines 1

Abstract

Conclusion

Glucosamine acetoacetate condensate or its salt form was isolated and identified by ultraviolet and infrared spectra and by gas chromatography from 12 out of 14 human diabetic urines; the condensate was not found in any of the 14 normal 3 urines. The isolated condensate preparations were also subjected to elemental analysis and found to have ratios of C:H:N corresponding with the standard condensate. These results indicate that the pyrrole condensate of glucosamine and acetoacetate occurs as a metabolite in patients with diabetes.