Abstract
Summary
Mestranol, a synthetic estrogen, causes significant increases in both leukocyte glycogen content and leukocyte alkaline phosphatase activity in dogs. Progesterone, by daily intramuscular injection, causes significant elevation of leukocyte alkaline phosphatase activity, but leukocyte glycogen content is unchanged.
This work was supported by the Blood Research Fund of the Mecical College of Virginia and Grant CA 08482-04 from the U. S. Public Health Service. Y. Abul-Fadl, M.D. was supported by a fellowship of the Leukemia Society of America, Inc. We thank LaVerne W. Cooper, Mary Vaughan, and Ronald Hamon for technical assistance, and Dorothy Barnes and Lucille Gouldin for expert secretarial assistance. We are indebted also to G. Watson James, III, M.D., for his support. Requests for reprints should be addressed to R. B. Scott, M.D.
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