Abstract
Summary
The activity of B.663 and ethionamide against Mycobacterium leprae in mice was determined at dosages of drug that varied by factors of 10. The minimal effective dosage of B.663 was 0.0001% in the diet: that of ethionamide was 0.01% in the diet. The very low minimal effective dosage of B.663 suggests that spaced ingestion or injection might be effective against leprosy in man.
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