Abstract
Summary
A very high degree of immune tolerance of C57B1/6J female mice to skin grafts from C57B1/6J male mice has been achieved by injection of splenic cells derived from skin donors into prospective recipients while they are in a state of pyridoxine deficiency. Equal numbers of splenic cells are much less effective in the production of immune tolerance when injected into control animals than when administered to pyridoxine-deficient recipients.
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