Abstract
Summary
The effect of cortisone on thyroidal 125I iodide uptake was investigated in hypophysectomized, pituitary-replaced, bilaterally nephrectomized rats. Cortisone reduced thyroid and body weights but did not reduce iodide uptake. Thus, an enhanced uptake of iodide per unit weight of gland resulted. It is unlikely that the enhanced 125I uptake resulted from a depletion of the extra-thyroidal iodide pool.
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