Abstract
Summary
Rats pretreated with disulfiram had a mortality rate of 23% when injected with 5 mEq/kg LiCl for 4 days. Some animals receiving lithium chloride in combination with disulfiram or asym. propylene glycol retained lithium in their serum and tissues at higher levels than those receiving only lithium chloride. Serum lactate was elevated in animals pretreated with disulfiram or receiving asym. propylene glycol and LiCl. No effect was found on brain 5-HT or tryptophan-5-hydroxylase and only slight effects on brain NE.
Get full access to this article
View all access options for this article.