Abstract
Summary
It has been suggested (1) that CG-P may serve as the metabolic hormone of pregnancy ensuring a maternal store of nitrogen and minerals and mobilizing fat.
CG-P (immunologically active fraction, after gel filtration) was injected intraperitoneally to hypophysectomized rats at a daily dose of 200 μg per rat during 10 days in order to demonstrate these actions.
The carcass composition of the animals was analyzed (water, fat, nitrogen, protein, and calcium).
A group of hypophysectomized rats which did not receive placental extract was used as control. The absence of changes in body composition in hypophysectomized rats treated with CG-P seems to indicate that under described experimental conditions, the placental protein does not have the postulated metabolic activities.
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