Abstract
Summary
A study of the relationship between virulence, peroxide formation, and cytadsorption in M. pneumoniae was undertaken. Two pairs of homologous virulent and attenuated strains were derived by passage of parent strains in animals and artificial media. Comparison of their cytadsorptive activity and peroxide formation by measurement of hemadsorption and hemolysis revealed variations between heterologous strains, but no differences consistently related to virulence. The existence of additional mediators of virulence is suggested.
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