Abstract
Summary
Incubation of hypotonic extracts of the light-mitochondrial fraction of kidneys from mammalian sources with sera of several vertebrate species resulted in the generation of erythropoiesis-stimulating activity only when duck or mammalian serum was used. Similar extracts of kidneys from carp, frogs, and ducks failed upon incubation with sera from the same species or from mammalian sources to generate an ESF active in the mammalian assay system. Incubation studies also revealed that no species specificity with regard to the REF-serum interaction existed among the members of the Class Mammalia tested.
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