In Vitro Incorporation of Formate- 14 C,Glycerol-1,3- 14 C,Choline-1,2 -14 C,Serine-1- 14 C,and Ethanolamine-1,2,- 14 C into the Major Phospholipids of Human Peripheral Arteries ∗

Abstract

Summary

The relative degrees of in vitro incorporation of ¹⁴C labeled precursors into surgical specimens of human femoral, tibial, and popliteal arteries were choline>ethanolamine>serine>formate>glycerol. Formate appeared to be incorporated primarily into phosphatidyl serine, probably by fixation to glycine. In addition to de novo synthesis, the pathway of transmethylation of phosphatidyl ethanolamine to phosphatidyl choline seemed to be operative in these arterial preparations.