Abstract
Summary
The fate of vitamin D3 in vitamin D-deficient rats was studied following the intravenous injection of 10 IU (0.25 μg) of [1, 2‐3H]‐vitamin D3 dissolved either in 0.05 ml of ethanol or 0.05 ml of blood plasma. Ethanol accelerates the disappearance of the radioactivity from the plasma compartment and decreases the characteristic rebound of plasma radioactivity occurring after 1–4 hr. The metabolic and toxic effects of ethanol are discussed, and the use of plasma as a vehicle for intravenous injections of vitamin D is advocated.
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