Abstract
Summary
Both DNase and lactic acid are able to liberate histories with antimicrobial activity from an inactive deoxyribonucleohistone complex. The type of histone was shown in both cases to be of a lysine-rich variety by amino acid analyses and acrylamide gel electrophoresis. Since both DNase and lactic acid would be expected to be present in an inflammatory foci, the significance of this model is emphasized.
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