Abolition of Milieu-Induced Hyperlipemia in the Rat by Electrolytic Lesion in the Anterior Hypothalamus ∗

Abstract

Summary

An electrolytic lesion placed in the anterior hypothalamus of rats fed 3 ml of cottonseed oil prevented the milieu-induced postprandial hyperlipemia usually observed in these animals. Thus the average 6-hr post-prandial plasma triglycerides (PTG) of the lesioned rats was 40 mg/100 ml and that of the controls was 91 mg/100 ml. A similar lesion placed in the tuberal area of the hypothalamus was not similarly effective.