Abstract
Summary
The water soluble constituents of cigarette smoke depress protein synthesis in rabbit alveolar cells in vitro. This effect is dose dependent, partly reversible, and greater than can be accounted for by the increase in acidity caused by addition of smoke solution to cell suspensions. It occurs at concentrations of smoke solution which do not affect cell viability or protein turnover. The major portion of this depressant activity is in the gas phase.
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