Abstract
Summary
Release of strain MC29 avian leukosis and Rous sarcoma (RSV) viruses by infected and/or morphologically altered chick embryo cells was measured by counts of physical particles and infectious units (FFU). Particles and FFU were liberated in parallel to a maximum rate at 3-4 days after low multiplicity culture inoculation. The ratios of particles/FFU, corrected for virus inactivation, were 878 and 232 for MC29 and RSV, respectively. Morphologically altered MC29 and RSV cells had a population doubling time of 24 and 42 hr, and the half-lives of the 2 agents were 6 and 10.5 hr, respectively, under simulated culture conditions.
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