Abstract
Summary
Precocious sexual receptivity and ovulation were induced in 22-day-old rats by injecting 3 IU of PMS, but the level of receptivity was low. Improvement in mating was obtained with 100 μg of progesterone and 2 μg of estradiol-17 β, administered on day 23 after a priming dose of 3 IU of PMS on day 22. This treatment postponed mating 1 day and induced ovulation in 98% of the animals. Delayed implantation was observed without administering steroids after mating in 29 of 56 rats examined for implantation sites.
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