Abstract
Summary
A natural conjugated estrogen preparation, Premarin, and a synthetic steroid, dl-13β-ethyl-3-methoxy-8α-gona-1,3,-5(10)-trien-17β-ol, at dietary concentrations of equal hypocholesterolemic activity, were equally effective in prolonging the lives of male rats fed a thrombogenic diet. The insignificant effect of the synthetic steroid on testicular weights demonstrated that antithrobogenic activity was dissociated to a large degree from feminizing activity.
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