Abstract
Summary
The occurrence of soluble inhibitors of tryptic and chymotryptic activity in extracts of human mixed astrocytic and oligodendrogliocytic glioma, solid and papillary ovarian adenocarcinoma, normal and adjacent infiltrating duct carcinoma of the breast, and normal and infiltrating carcinoma of the cecum are reported. The inhibitors are nondialyzable and heat labile. On the basis of such properties, the inhibitors differ from the Northrop and Kunitz inhibitor, the Kazal inhibitor, the colostrum inhibitor, and the inter-alpha-and alphaz-globulins found in mammalian tissue.
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