Abstract
Summary
Exposure of small inocula of microorganisms on the surface of blood agar medium to high pressure oxygen (HPO; 100% O2 at 3 atmospheres absolute) has provided a simple direct method for quantitating its antibacterial effect upon 102 strains from among 20 microbial species. The bactericidal effect was dependent upon the duration and intensity of exposure to HPO, and was independent of common taxonomical characteristics such as cellular morphology, gramstaining reaction, and a strict or facultative growth requirement for normobaric oxygen.
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