Abstract
Summary
Rat thyroid has a high concentration of calcium which is known to decline with thiourea treatment and increase with inanition or a high calcium-low iodine diet. The histochemical localization of this calcium in normo- and hyper calcemic states was studied. Use of glyoxal bis(2-hydroxyanil) and alizarin red S revealed localization in the follicular cells. Rats rendered hypercalcemic by increase in dietary calcium or by injections of dihydrotachysterol showed virtually identical structural and histochemical appearance of their thyroids as those of control animals.
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