Abstract
Summary
The transport of 3-O-methyl-D-glucose was studied in 20-cm segments of upper jejunum removed with an intact circulation from the animal and perfused extracorporeally. Intestinal preparations from alloxanized animals had a significantly higher percentage minute absorption of the substrate. Insulin failed to modify the transport rate in both the control and the alloxantreated animals. However, insulin stimulation of transport was observed in experiments carried out in a group of rats where diabetes was induced by anti-insulin serum.
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