Abstract
Summary
Cycloheximide, at a dose (0.5 mg/kg, i.m.) which is known to inhibit incorporation of amino acids in the proteins of the stomach was found to decrease gastric secretory volume and acid and pepsin production in rats with pylorus ligation. When various stimuli to gastric secretion (alcohol, insulin, gastrin pentapeptide, and 2-deoxyglucose) were given, there were smaller absolute responses in the cycloheximide-treated rats than in controls.
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