Abstract
Summary
The production of porphobilinogen and porphyrins by spleen extracts of Friend virus (FV) infected mice depends on the initial enzymic activity in the organ and varies with the amount of virus injected and the strain of mice employed. The increase in the enzymic activity appears to be as sensitive a measure of FV infection as was the splenomegalic response. Only minor changes in the enzymic activity were observed during the development of splenomegaly induced by leukemia L1210.
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