Abstract
Summary
Lard was given orally to rats 6 days and 6 weeks after alloxan administration and to insulin-treated alloxanized rats 6 days and 6 weeks after insulin withdrawal. Two hr after the fat feeding serum FFA and blood ketone concentrations were determined. The blood ketone concentrations were higher but serum FFA levels were lower in the acutely than in the chronically insulin deficient rats. The results indicate that in alloxan diabetic rats the degree of ketonemia is not proportional to the level of serum FFA but seems partly to depend on the duration of insulin deprivation.
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