Abstract
Summary
Anti-HCG cross-reacted with rat pituitary LH resulting in the formation of soluble complexes which were biologically active as measured by the OAAD bioassay. Pituitary glands from castrated rats, presumably containing elevated levels of LH, showed an increased number of hypertrophic fluorescent positive cells. Conversely, pituitary glands from rats which had received either diethylstibestrol or testosterone cy-clopentylpropionate for 1 month, treatments expected to result in lowering of pituitary LH content, showed minimal fluorescence. These observations strongly suggest that the immunofluorescent-positive cells contain rat LH.
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