Abstract
Summary
Plasma 17-OHCS response to ACTH in M. mulatta of 2.5-8years of age has been found to average 18 μg/100 ml in the first hour and to increase more slowly subsequently, achieving a maximum rise of about 50 μg/100 ml in 4 or more hr. The response was 3-fold higher in infants, 2-fold higher in monkeys of 6 and 15 months of age. and only 60% as high in 15-year-old monkeys. There was no significant correlation of the response with weight, nor was there any significant sex difference except perhaps in male laboratory-reared monkeys in which the response was only 60% that of adult feral-reared monkeys or female laboratory-reared monkeys.
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