Abstract
Summary
The IgM cold agglutinins were produced by intravenous injection of heat killed L. monocytogenes 4b into rabbits heterozygous (b4b5 ) for the light polypeptide chains of immunoglobulins. The radiolabeled cold agglutinins were analyzed for the b4 and b5 allotypes. The percentage of b4 and b5 light chains precipitable was independent of the order of precipitation with anti-b4 and anti-5 indicating that the cold agglutinin IgM molecules carry either the b4 or b5 light chain but not both.
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