Abstract
Summary
Buffy coat cells obtained from the blood of 11 patients with infectious monucleosis were inoculated into selected rhesus monkeys and marmosets. These monkeys were free of detectable complement-fixing antibodies to a herpes-like virus (EBV) considered to be etiologically related to infectious mononucleosis. None of the inoculated animals developed detectable illness, or hematological and serological changes. Attempts to isolate a viral agent from the throats of the 11 patients in cultures of human leukocytes were unsuccessful.
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