Abstract
Our experiments were made upon etherized cats. We injected secretin at intervals and determined that equal doses of secretin were followed by equal increments in the bile secretion. The cystic duct was previously ligated close to the common duct into which a glass cannula was inserted. After determining the effect of a dose of secretin, we waited some time and then injected an equal dose of secretin plus the infusion of the animal extract. The drops of bile were counted for five-minute periods. We found that adrenalin and the hypophysin of Fühner (pituitrin) greatly slowed the secretion. Pancreas slightly diminished the secretion. Thyroid extract had hardly any effect. Tonsil extract caused a marked increase. Thymic extract decreased it. Parathyroid, mammary and corpus luteum had no action.
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