Abstract
Chickering found that sodium carbonate extracts of a precipitate, produced by a mixture of pneumococcus substance and its antiserum, contained agglutinating and protective antibody, but no antigen. If precipitates produced by the combination of horse serum, or egg albumen, and their respective antiserums, be treated with salt solution, or with 1 per cent. sodium carbonate, the resulting extract always contains antigen. It also contains passively sensitizing antibody, but no precipitin.
If such a precipitate be treated with trypsin, or with rabbit's leucocytes, both antigen and precipitin are present in the extract. Sensitizing antibody is also demonstrable.
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