Abstract
Summary
Addition of 1% orotic acid to a choline-deficient diet lowered the incidence of hemorrhagic renal necrosis in young rats from 86% to 41%, and within 24 hr prevented the accumulation of hepatic triglycerides by almost 50%. Simultaneous supplementation of the diet with 0.25% adenine sulfate did not influence these protective effects of orotic acid in choline deficiency.
Get full access to this article
View all access options for this article.