Abstract
Summary
Incubation of slices of rachitic epiphyseal cartilage of rats in trypsin, chymotrypsin, pronase, and hyaluronidase resulted in a loss of calcifiability, as determined by subsequent incubation in calcifying solutions. It is concluded that breakdown of glycosaminoglycan-protein, per se, in cartilage is not a sufficient condition to make the tissue calcifiable.
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