Abstract
Summary
In searching for an animal model for human adenovirus studies we have attempted to infect rhesus monkeys with a human type 4 adenovirus. The results were inconclusive but we have some evidence to suggest that infection and replication might have occurred in several animals. Communicability among cagemates was not demonstrated. The difficulty encountered in infecting rhesus monkeys despite the large virus dose employed indicates that this animal would not serve as a useful model for vaccine testing.
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